soloMERs™ are superior to and differentiated from more traditional antibody platforms as they are pre-disposed to bind novel or cryptic epitopes (“canyon-binders”), seeking out pockets or grooves in protein targets. soloMERs can deliver the equivalent neutralising potency as antibodies, but from a protein only 9% their size.
Their simple modular formats express well in both prokaryotic and eukaryotic systems. soloMER re-formatting is “plug-n-play” with bi and tri-specificity and/or bi-paratopic potency achievable with a final molecular weight of only 25 – 35 kDa.
