Half-Life Extension

NDure™ is a soloMER (humanized clinical candidate) available for extending the plasma half-life of fused partner molecules such as scFv, peptides, growth factors, single domains etc. NDure binds to human serum albumin with high affinity and selectivity and has demonstrated efficacy across three PK models.  NDure extends the serum half-life of companion proteins including therapeutic soloMERs (fused to either/both N and C terminals) from a few hours to several days giving a predicted half-life of 19 days in man.

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